Garlic-Based Remedy For Hair Loss

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Garlic for treating hair loss is one that I found during my experience with hair loss, a solution that I finally got to him, when I tried other means failed.

I turned to home remedies for hair loss, since none of the conventional medicines helped.

This is by far the best remedy for hair loss that I tried and I tried many. I also had the courage to use vaseline on my hair, and thathad to say it gently, not a very wise choice. And ‘certainly helped with the removal of dead cells from my scalp, because it burns the skin.

Then you must not be tempted to the same thing I did, try this garlic remedy for hair loss do to

Ingredients:

1 tablespoon of aloe gel

1 tablespoon honey

1 tablespoon garlic juice

2 egg yolks

3 tablespoons of chamomile (tea bag content is easy to use)

24 oz fluidWater

Instructions:

1) Peel the garlic and use a garlic press to squeeze the juice

2) Mix with honey and place the bowl in the refrigerator

3) Boil water with chamomile tea for about 30 minutes

4) Stir occasionally

5) When the tea is ready, remove the bowl with the honey and the juice of garlic from the fridge

6) Mix the egg yolk in garlic juice / honey mix

7) The gel of aloe.

with the mixture and rub gently into your scalp. If you are from the , Adding a towel around his head.

Keep 9) in the head for 20 minutes and washed once with a neutral shampoo (I Johnson) ‘s baby shampoo. Rub the egg yolk seconds and rinse with lukewarm water.

10) Finally, wash the hair with previously prepared chamomile tea.

Use this mixture once a week. If you notice any improvement within a month or so, you can visit a dermatologist.

That’s it! This may seem a little ‘complicated, but remember: your> Hair loss is a complex issue and deserves to be treated like one. Let me know if you find these resources useful for hair loss.

Cause of Hair See 7ped.com

laser hair brush Blog: laser hair brush


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Preventing Hair Loss Can be Easier Than You Think

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Hair loss is a concern of many people, even people who still have their hair. They worry about losing their hair, how they would look, what people would think of them and many other concerns. A lot of these people have seen other people in their family suffer from hair loss and worry they are next. Preventing hair loss is doable in certain circumstances.

 

Many people who have parents that are balding are worried they will suffer from hair loss as well. Hereditary hair loss is called androgenic alopecia or male pattern baldness and female pattern baldness. This type of hair loss affects men and women differently but can be equally devastating. The best way of preventing this is to know if you will end up with it. There are new DNA test that can be done to determine if you have the gene that leads to androgenic alopecia. Once you know that you do carry this gene, you will know to be watchful of the first signs. At the very beginning, you can get laser therapy to get your hair loss corrected. This treatment will increase blood flow to the scalp and help you to retain the hair you have. The key thing with this form of treatment is to catch it while it is in the early stages. Once the follicles have died off, there is no saving them.

 

Another essential to preventing hair loss is making sure you receive the proper nutrients your body requires to keep your hair healthy. This means getting plenty of B vitamins, plenty of iron and protein, magnesium, zinc, copper, silica and even vitamins C and E. These vitamins and minerals will ensure that your body has everything it needs to keep your hair growth cycle operating, as it should. You can accomplish this by sticking to a low fat and high protein diet and taking a multivitamin designed specifically for healthy hair, skin and nails. Proper nutrition is essential, not only for healthy hair, but also for a healthy body as well. Your hair says a lot about your health. Having unhealthy hair that is falling out, shows that your body is unhealthy.

 

When you want to prevent hair loss there are also a few simple tips to keep in mind. The first is not to wear your hair in tight hairstyles, such as braids and ponytails, for extended periods of time. This can cause you to lose your hair. Another tip is to watch your stress levels. High stress can make your hair fall out as well. So find ways to minimize your stress. Massage is a great way to help with this. Massage can help improve the function of all your different body systems. Follow these simple tips to help prevent hair loss. If you are truly concerned about hair loss, talk to your doctor. He or she can help keep an eye on your hair and give you advise on other ways to help prevent your hair loss.

 

Are you looking for the best Treat Baldness ?  Visit http://www.baldness-prevention.com today for more information!


Article from articlesbase.com

More Prevent Hair Loss Articles

Preventing Hair Loss Can be Easier Than You Think

Posted on by

Hair loss is a concern of many people, even people who still have their hair. They worry about losing their hair, how they would look, what people would think of them and many other concerns. A lot of these people have seen other people in their family suffer from hair loss and worry they are next. Preventing hair loss is doable in certain circumstances.

 

Many people who have parents that are balding are worried they will suffer from hair loss as well. Hereditary hair loss is called androgenic alopecia or male pattern baldness and female pattern baldness. This type of hair loss affects men and women differently but can be equally devastating. The best way of preventing this is to know if you will end up with it. There are new DNA test that can be done to determine if you have the gene that leads to androgenic alopecia. Once you know that you do carry this gene, you will know to be watchful of the first signs. At the very beginning, you can get laser therapy to get your hair loss corrected. This treatment will increase blood flow to the scalp and help you to retain the hair you have. The key thing with this form of treatment is to catch it while it is in the early stages. Once the follicles have died off, there is no saving them.

 

Another essential to preventing hair loss is making sure you receive the proper nutrients your body requires to keep your hair healthy. This means getting plenty of B vitamins, plenty of iron and protein, magnesium, zinc, copper, silica and even vitamins C and E. These vitamins and minerals will ensure that your body has everything it needs to keep your hair growth cycle operating, as it should. You can accomplish this by sticking to a low fat and high protein diet and taking a multivitamin designed specifically for healthy hair, skin and nails. Proper nutrition is essential, not only for healthy hair, but also for a healthy body as well. Your hair says a lot about your health. Having unhealthy hair that is falling out, shows that your body is unhealthy.

 

When you want to prevent hair loss there are also a few simple tips to keep in mind. The first is not to wear your hair in tight hairstyles, such as braids and ponytails, for extended periods of time. This can cause you to lose your hair. Another tip is to watch your stress levels. High stress can make your hair fall out as well. So find ways to minimize your stress. Massage is a great way to help with this. Massage can help improve the function of all your different body systems. Follow these simple tips to help prevent hair loss. If you are truly concerned about hair loss, talk to your doctor. He or she can help keep an eye on your hair and give you advise on other ways to help prevent your hair loss.

 

Are you looking for the best Treat Baldness ?  Visit http://www.baldness-prevention.com today for more information!


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Best Vitamins for Hair Growth and Great Hair Loss Treatment

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The best vitamins for hair growth include the B vitamins. These are usually found in whole grains, fresh fruit, brewer’s yeast, eggs, fish, turkey, meat, and milk.

These vitamins are water-soluble, which means they don’t build up in your body like vitamin A does.

•    Para-aminobenzoic acid may prevent your hair from graying.
•    Inositol can help prevent hair loss.
•    Niacin (vitamin B-3) promotes blood circulation to your scalp.

Vitamin B

B vitamins are especially important for hair growth and maintenance and are considered as the best vitamins for hair growth.

Vitamin B is a complex vitamin that can be sub-divided into different types like vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B7 (biotin), vitamin B9 (folic acid), and vitamin B12 (cyanocobalamin).

Vitamin A

Vitamin A, also known as Retinol, plays an important role in building new cells and tissues in the body, including hair.

Vitamin A is also essential for overall normal growth of the body and helps in maintaining healthy skin, hair and nails. Vitamin A also plays an important role in keeping the hair follicles lubricated.

Have you ever taken a good, long look at the ingredients in some of the top hair products? Most of them are filled with hair growth vitamins and other vitamins that are meant to make the hair shiny and thick.

It makes sense, then, that when you are looking for a re-growth treatment, you would want to search for one that uses hair growth vitamins.

Hair Growing Tips

1. Eliminate or cut back on smoking, caffeine and carbonated sodas which weaken the body and block maximum hair growing potential.

2. Eat a healthy diet.  Avoid foods that are high in sugar or fat.

3. Treat your hair like a piece of fine old lace.  Treat it carefully avoiding any unnecessary brushing, combing or handling.

4. Avoid use of hot water, hot blow dryers or other hair care tools that may stress the hair.

5. Have a weekly scalp massage to provide stimulation to the hair follicles.

6. Do a series of ongoing hot oil treatments to protect the hair’s shaft.

Home Remedies for Hair Loss

Preparing hair tonics isn’t something new. There are literally hundreds of home remedies with recipes on how to prepare your very own hair tonics. Amla oil boiled with coconut oil is just one example.

Mixing amla juice and lime juice.

The two comes together to become an successful hair loss prevention formula.

This is one of the easiest method. There is no boiling, and no cooking. All that is needed, is to extract the fresh juices, and use them with your shampoo when you wash your hair.
Consuming lettuce and spinach juice.

Improving the general health of the body creates the conditions that are conducive for hair growth. Eating green vegetables or consuming vegetable juices is one way to boost the immune system of the body.

When you consume juices that come from lettuce and spinach, your body absorbs the nutrients and vitamins without difficulty and that helps to promote hair growth.

Lime seeds and black pepper.

Grind lime seeds and black intersperse (in equal proportions) and use the paste as a hair tonic. Apply the paste thinly on the scalp on a daily basis.

Leave it on for about ten to fifteen minutes, and then rinse it off with water and mild shampoo. Be careful not to get any of the substances in your eyes though!

ErectifyXL.com Dr. discusses ED and the best vitamins to help erectile dysfunction. If you’re interested in fixing erectile dysfunction, then watch this video right now!

About Male Pattern Baldness And Its Treatments

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Male pattern baldness, scientifically known as androgenetic alopecia is one of the most common causes of hair loss in men. A large number of men experience this condition in their middle ages; however, some men may experience male pattern baldness at a much early age. In this condition, hair is lost in a well-defined pattern beginning above both temples. Hair also thins at the crown of the head. Male pattern baldness often progresses to partial or complete baldness in men.

Phases of male pattern baldness

Our hair follicles are divided into two phases, that is the growing phase and the resting phase. Almost 90% of our hairs are in growth phase, which lasts for approximately 4 to 5 years. During the growth phase, our hairs grow in length. Once the hairs are fully grown, the resting phase starts, which lasts for up to 4 months. After this period, the old hair falls out completely and in natural course these are replaced by new hair. This is an ongoing process in which we may lose up to 100 hairs daily. However, in men suffering from male pattern baldness, hair fall increases at an alarming rate; the new hairs that replace the old ones come slowly or are too thin.

According to experts, men should begin treatment for male pattern baldness as soon as they notice this problem. Beginning the treatment early helps to check further hair loss and treat the condition more effectively.

How to cure male pattern baldness?

While many men choose to live with the condition, others try all sorts of cures advertised over the internet and in the media. Some of the popular treatment options available for male pattern baldness include:

Use of herbal shampoos and oils – There are large number of herbal shampoos and oils available on the market; each claim about giving guaranteed treatment. However, their effectiveness has not yet been proven.

Minoxidil solution – Available over the counter by the trade names of Rogaine and Regaine, minoxidil helps to slow down or stop hair loss as well as promote hair regrowth. However, this medicine has shown limited success and many people find it uncomfortable to use.

Propecia finasteride – This is by far one of the most effective medications available for the treatment of male pattern baldness. Propecia finasteride was approved by the FDA in1997 as a prescription treatment for male pattern baldness. Propecia is available in a pill form which is to be taken orally once a day.

How effective is Propecia to treat male pattern baldness?

Propecia is the most effective treatment that is currently available for male pattern baldness. Studies have shown that almost 80% of men using Propecia stopped or even reversed their hair loss to a certain degree. However, for the benefits to continue, you will need to take the pill everyday. Once you stop the treatment, hair gained during the treatment will be lost within one year. To get effective results you should begin the treatment early. Propecia finasteride is to be used by men only. It should never be used by women and children.

Hayden Eck – Health Adviser and Webmaster of online health clinic AtlanticDrugs.com, has been providing health newsletters and articles since last 5 years. He has also provided vital information for consultation of prescription treatments like Propecia (finasteride) a male pattern baldness treatment pill at AtlanticDrugs.


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Male Pattern Baldness-Causes, Symptoms, Treatments

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Male pattern baldness is the most common type of hair loss in men. It usually follows a typical pattern of receding hairline and hair thinning at the crown; this is primarily caused by hormones and genetic predisposition.

Causes of male pattern baldness?

Most men suffering from premature hair loss are genetically predisposed to androgenetic alopecia, also known as male pattern baldness. Male pattern baldness occurs due to the action of testosterone – the primary male sex hormone – on your hair follicles. Present in high amounts after puberty, testosterone is converted to dihydrotestosterone (DHT) because of 5-alpha reductase – an enzyme present in your body. Working on the hormone receptors present in your hair follicles, DHT retards the production of scalp hair and produces shorter and weaker hair, and sometimes prevents hair growth completely. This is a gradual process which eventually results in total or partial hair loss.

Since male pattern baldness is largely a genetic condition, the negative effects of DHT and testosterone on your hair growth will be determined by your genetic inheritance from both sides of the family. It is thus possible to know the extent of hair loss you are likely to suffer by studying your family’s tendency to baldness. This is important so that you are able to predict the pattern and course of your baldness and seek appropriate medical treatment to minimize the inevitable loss of hair.

Symptoms of male pattern baldness

The typical process of male pattern baldness usually starts at the hairline, which recedes in the form of an ‘M’ shape. Your existing hair also tends to become thinner and finer in quality. The hair on your crown starts thinning until it meets your hairline, leaving behind a horseshoe pattern at your temples. Male pattern hair loss is also characterized by patchy and diffused hair loss, breakage of hair shafts, and is sometimes accompanied by scaling, redness or pain.

Who does male pattern hair loss affect?

You suffer from male pattern hair loss when specific areas on your scalp are hyper-sensitive to testosterone present in your body. These hormones make your hair follicles shrink gradually till they become too small to have the ability to replace lost hair. These hair follicles are alive but totally incapable of doing their job. This condition usually affects genetically predisposed men between the ages of 20-30. The pattern and amount of hair loss you experience varies greatly, ranging from conditions such as androgenetic alopecia (also known as alopecia androgenetica), alopecia areata (involving a certain amount of hair loss), alopecia totalis (complete hair loss from your head) and alopecia universalis (complete hair loss from your head and the rest of the body).

Male pattern hair loss treatment options

Although, it cannot be completely cured, there are a number of non-surgical treatments for male pattern hair loss. You need to choose a treatment based on the degree and pattern of hair loss you suffer from. Non-surgical hair replacement therapy simulates the natural appearance of hair and offers enhanced density of overall hair. Surgical hair transplants use micro-grafting for creating a natural-looking hairline. There are a number of medications such as prescription Propecia that help in promoting hair growth and preventing further hair loss. You can also opt for laser hair replacement therapy to regain lost hair.

John is one of the good article writers having much experience in writing health articles. He has written many articles on Propecia Finasteride for male pattern hair loss treatment.Propecia Online can be got from an online pharmacy over internet


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Male Pattern Baldness Treatments: Do They Really Work?

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The statistics are quite staggering, by the time they reach the age of 50, 50% of the worlds’ male population are affected by male pattern baldness. Many men just accept this and get on with life, but more men are learning about the newly affordable male pattern baldness treatments and want to keep their crowning glory. These new treatments started becoming available over fifteen years ago, but unless you were quite well off cost was always a major prohibiting factor (John Travolta was reported as spending around 00 a month for his treatment). Now prices are down to a level where most people can afford high quality treatments and if started early enough there is no reason why you should ever go bald. Having said that it should be made clear that there are still no miracle cures, if you are now completely bald there is still very little that can be done apart from wearing a hairpiece. But treatments can be very effective in re-growing hair for some people. It is a matter of learning what is possible and setting your expectations accordingly. There are a few things you should know before seeking a particular type of treatment. It is firstly important to understand why male pattern baldness occurs and how it develops before deciding which of the currently available treatments is right for you.

Why Hair Loss Occurs

Male pattern hair loss, also known as androgenetic alopecia is a genetically predetermined condition. The main contributing factor for causing it is the male hormone testosterone, hence this is why few females suffer from the condition and why castrated males never go bald. But testosterone does not directly cause hair loss, it interacts with an enzyme called 5-alpha reductase to produce the real culprit, a derived hormone called dihydrotestosterone (DHT). DHT is widely acknowledged to be the main cause of hair loss in men. Men lucky enough not to go bald have hair that is resistant to the effects of DHT.

Topical Application

Now that it is known what causes male pattern baldness many hair loss shampoos have been developed specifically to remove DHT from the scalp. These types of products are deep cleansing agents known as DHT blockers and have been used effectively to stop further hair loss and provide the optimum conditions to stimulate new hair growth. You may have heard of Minoxidil male pattern baldness treatment, this is not a DHT blocker, it is thought to work by directly stimulating cell growth in the hair follicle thereby giving it a resistance to DHT. The results though are the same and because they work differently, Minoxidil and DHT blockers can be used together for an even more effective hair loss treatment.

Internal Drugs

One of the most effective oral medications for treating hair loss was discovered accidentally when developing a cure for enlarged prostate gland in men. This drug was finasteride and it was found that in low doses finasteride was effective in preventing of male pattern baldness. It is now one of very few drugs with FDA approval for the prevention and treatment of male pattern baldness and only available on prescription.

As a natural alternative to Finasteride, a herb called Saw Palmetto is often claimed to be able to reduce DHT and therefore prevent male pattern balding. There are now many natural male pattern baldness treatments that contain saw palmetto and while only small scale clinical trials have been conducted results have been positive.

Transplants

As a last resort hair transplantation may be the only option for men with a bald patch greater than about ten centimetres (4 inches). This generally involves removing a doner strip of scalp from the neck area and grafting doner follicles to the bald patch. Scalp reduction is another surgical procedure where the bald scalp area is removed altogether with the remaining scalp skin pulled together. While this may seem quite drastic it can be a quite effective procedure in removing small bald patches

Conclusions

For many men baldness is accepted as part of the aging process and they adapt gracefully to their new look. But with many new male pattern baldness treatments available, men now have a choice in preventing hair loss altogether if they act early enough. The treatment is often needed for life but for many men that could be one of the best investments they ever make!

Please visit our web site for more information and advice on how to stop thinning hair.

John Tulley has written many articles on the subject of hair loss treatments and remedies. To read further articles by John Tulley click here: Hair loss directory.

To download a free copy of John Tulleys’ brand new e-book, “Hair Loss Treatments: How to Stop Hair Loss and Regrow Your Hair!”, click here: Hair Loss Treatments Report


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How to Prevent Hair Loss Thinning

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Hair loss thinning is a problem that affects millions of people. That means men and women alike. However with advances in science, we can now figure out the cause of hair loss. This helps to not only know how to reverse the hair loss but prevent it as well. Preventing hair loss is a miracle some people have been waiting for.

 

The most common form of hair loss thinning is androgenic alopecia, which is male pattern baldness and female pattern baldness. This is a hereditary condition in which your body turns testosterone into DHT or dihydrotestosterone. While testosterone makes hair grow, DHT has the opposite affect and makes you lose your hair. Scientists have figured out how to narrow downthe gene that causes androgenic alopecia. This is helpful in preventing hair loss because you can have a DNA test run on your hair to see if you carry the gene that causes this condition. This test will not tell you whether you will go bald or not. It only tells you if you carry the genetic markers that cause male pattern baldness and female pattern baldness. There are many forms of hair loss and this is just one of the casues. So just because you do not cary the gene, does not mean you will live your life with a full head of hair and no worries.

 

Knowing the conditions you have that can casue hair loss is another way you can help prevent hair loss. Conditions such as autoimmune disorders, thryroid problems and even diabetes can cause hair loss. Even medications you are taking for your condtions can cause hair loss. The best thing you can do is talk to your doctor and see if anything you are taking or any conditions you may have can cause you to lose your hair. Discuss your concerns over hair loss with your doctor. He or she can help keep an eye on it and give you the best advice on how to treat the issue.

 

One of the best solutions to preventing hair loss thinning though is proper nutrition. Your body needs the right vitamins and minerals to make sure that it functions properly and your hair is no difference.  Even though protein is the main component of hair, it is not the only nutrient your body need. You need to have plenty of Bvitamins, magnesium, zinc, copper, vitamin C and E and many others. A good diet with this is important as well to keeping your hair. Studies have shown a correlation between high fat diets and hair loss. Therefore, your best solution is to eat a diet low in fat and high in protein in conjunctions with a mutivitamin supplment for healthy hair.

 

Knowing the risk factors for hair loss is the best place to start. Watch for early signs of balding and makesure f it starts you seek treatment as  soon as possible. This will help you keep the hair you have and can even help reverse the hair loss as well.

 

Are you looking for the best Treat Baldness ?  Visit http://www.baldness-prevention.com today for more information!


Article from articlesbase.com

How to Prevent Hair Loss Thinning

Posted on by

Hair loss thinning is a problem that affects millions of people. That means men and women alike. However with advances in science, we can now figure out the cause of hair loss. This helps to not only know how to reverse the hair loss but prevent it as well. Preventing hair loss is a miracle some people have been waiting for.

 

The most common form of hair loss thinning is androgenic alopecia, which is male pattern baldness and female pattern baldness. This is a hereditary condition in which your body turns testosterone into DHT or dihydrotestosterone. While testosterone makes hair grow, DHT has the opposite affect and makes you lose your hair. Scientists have figured out how to narrow downthe gene that causes androgenic alopecia. This is helpful in preventing hair loss because you can have a DNA test run on your hair to see if you carry the gene that causes this condition. This test will not tell you whether you will go bald or not. It only tells you if you carry the genetic markers that cause male pattern baldness and female pattern baldness. There are many forms of hair loss and this is just one of the casues. So just because you do not cary the gene, does not mean you will live your life with a full head of hair and no worries.

 

Knowing the conditions you have that can casue hair loss is another way you can help prevent hair loss. Conditions such as autoimmune disorders, thryroid problems and even diabetes can cause hair loss. Even medications you are taking for your condtions can cause hair loss. The best thing you can do is talk to your doctor and see if anything you are taking or any conditions you may have can cause you to lose your hair. Discuss your concerns over hair loss with your doctor. He or she can help keep an eye on it and give you the best advice on how to treat the issue.

 

One of the best solutions to preventing hair loss thinning though is proper nutrition. Your body needs the right vitamins and minerals to make sure that it functions properly and your hair is no difference.  Even though protein is the main component of hair, it is not the only nutrient your body need. You need to have plenty of Bvitamins, magnesium, zinc, copper, vitamin C and E and many others. A good diet with this is important as well to keeping your hair. Studies have shown a correlation between high fat diets and hair loss. Therefore, your best solution is to eat a diet low in fat and high in protein in conjunctions with a mutivitamin supplment for healthy hair.

 

Knowing the risk factors for hair loss is the best place to start. Watch for early signs of balding and makesure f it starts you seek treatment as  soon as possible. This will help you keep the hair you have and can even help reverse the hair loss as well.

 

Are you looking for the best Treat Baldness ?  Visit http://www.baldness-prevention.com today for more information!


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How Insulin Resistance May Play Role In Hair Loss

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Insulin resistance and its role in diabetes has been known for decades and much research has led to advancements in Type II diabetic therapy.

There are many known possible factors of developing diabetes. It has increasingly been found that that hair loss in some people may be due to insulin resistance and the topic is being studied by many leading hair loss research centers especially for cases of scarring alopecia.

Recent research by Pratima Karnik, Ph.D., and investigators at Case Western Reserve University in Cleveland and the University of California, San Francisco, found that the initiating event in the pathogenesis of scarring alopecia may be loss of peroxisome proliferator-activated receptor gamma function aka ppar-y. Their finding paves the way for clinical trials testing the hypothesis that peroxisome proliferator-activated receptor (ppar)-gamma upregulation may offer a novel means of treating scarring alopecia. The ppar-gamma agonists, thiazolidinediones and glitazones, are prescribed for glycemic control in patients with type 2 diabetes.

“This work about ppar-gamma is just so exciting. In just the next year or two, it could [make a difference] in the way we treat patients with cicatricial alopecia,” said Dr. Kenneth Washenik at the annual meeting of the American Academy of Dermatology.

“This is a really, really important milestone paper,” said Dr. Washenik, a dermatologist at New York University and medical director at Bosley Medical, the nation’s largest hair restoration group.

The ground-breaking report included several related studies (J. Invest. Dermatol. 2008;129:1066-70). In one, the investigators performed gene microarray analysis using scalp biopsy specimens from patients with lichen planopilaris (LPP)–an inflammatory scarring hair disorder–and from normal controls. LPP patients had reduced expression of genes required for lipid metabolism and production of peroxisomes.

Immunohistochemical studies in lesional and uninvolved skin of LPP patients showed progressive loss of ppargamma activity and local accumulation of unprocessed lipids.

These lipids appeared to be proinflammatory. In areas of lesional skin they were accompanied by production of proinflammatory cytokines and infiltration of inflammatory cells, followed by the hallmark of LPP: the destruction of sebaceous glands and hair follicles, with resultant scarring.

The investigators also showed that ppar-gamma agonists induced peroxisomal and lipid metabolic gene expression in keratinocytes.

The clincher in making a case for loss of ppar-gamma function being the key initiating event in the pathogenesis of LPP–and by inference in the other cicatricial alopecia as well involved the investigators’ work with transgenic mice. The team created a knockout mouse model lacking ppar-gamma in follicular stem cells. These mice gradually developed a progressive scarring alopecia beginning at about age 4 weeks, with complete scarring alopecia by 4 months.

The mouse’s scarring alopecia looked histologically just like LPP: dystrophic hair follicles, follicular plugging, perifollicular fibrosis, and, most importantly, dystrophic sebaceous glands with perifollicular and interstitial inflammation.

Dr. Washenik noted that these new LPP studies are merely the latest in a series of reports suggesting a variety of potential dermatologic applications for glitazones.

Official author and natural hair loss expert. Natural hair loss treatments, prevention, dht, and alopecia reviews, stories, and studies can be found at Zenagen natural hair loss shampoo website and up to date hair loss news at the hair loss blog.


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